帝京大学
鈴木 利宙

鈴木 利宙 講師

所属キャンパス板橋キャンパス

研究所・センター 医療共通教育研究センター

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経歴・所属学会・専門分野・研究テーマ

所属学会

日本免疫学会

日本癌学会

教育方法・職務上の実績

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著書・論文

学術論文

Imaizumi K, Suzuki T, Kojima M, Shimomura M, Sakuyama N, Tsukada Y, Sasaki T, Nishizawa Y, Taketomi A, Ito M, Nakatsura T

Ki67 expression and localization of T-cells after neoadjuvant therapies as reliable predictive markers in rectal cancer.

2019年10月 | Cancer science  

学術論文

Shitara K, Ueha S, Shichino S, Aoki H, Ogiwara H, Nakatsura T, Suzuki T, Shimomura M, Yoshikawa T, Shoda K, Kitano S, Yamashita M, Nakayama T, Sato A, Kuroda S, Wakabayashi M, Nomura S, Yokochi S, Ito S, Matsushima K, Doi T

First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors.

2019年07月 | Journal for immunotherapy of cancer 7 1 195 

学術論文

Okada M, Tada Y, Seki T, Tohyama S, Fujita J, Suzuki T, Shimomura M, Ofuji K, Kishino Y, Nakajima K, Tanosaki S, Someya S, Kanazawa H, Senju S, Nakatsura T, Fukuda K

Selective elimination of undifferentiated human pluripotent stem cells using pluripotent state-specific immunogenic antigen Glypican-3.

2019年04月 | Biochemical and biophysical research communications 511 3 711-717 

学術論文

Akazawa Y, Mizuno S, Fujinami N, Suzuki T, Yoshioka Y, Ochiya T, Nakamoto Y, Nakatsura T

Usefulness of serum microRNA as a predictive marker of recurrence and prognosis in biliary tract cancer after radical surgery.

2019年04月 | Scientific reports 9 1 5925 

学術論文

Prospects for immunotherapy as a novel therapeutic strategy against hepatocellular carcinoma.

2019年03月 | World J Metaanal. 7 3 80-95 

学術論文

Shimizu Y, Suzuki T, Yoshikawa T, Endo I, Nakatsura T

Next-Generation Cancer Immunotherapy Targeting Glypican-3.

2019年 | Frontiers in oncology 9 248 

学術論文

Takahashi D, Kojima M, Suzuki T, Sugimoto M, Kobayashi S, Takahashi S, Konishi M, Gotohda N, Ikeda M, Nakatsura T, Ochiai A, Nagino M

Profiling the Tumour Immune Microenvironment in Pancreatic Neuroendocrine Neoplasms with Multispectral Imaging Indicates Distinct Subpopulation Characteristics Concordant with WHO 2017 Classification.

2018年09月 | Scientific reports 8 1 13166 

学術論文

Shashni B, Ariyasu S, Takeda R, Suzuki T, Shiina S, Akimoto K, Maeda T, Aikawa N, Abe R, Osaki T, Itoh N, Aoki S

Size-Based Differentiation of Cancer and Normal Cells by a Particle Size Analyzer Assisted by a Cell-Recognition PC Software.

2018年04月 | Biological & pharmaceutical bulletin 41 4 487-503 

学術論文

Shimizu Y, Suzuki T, Yoshikawa T, Tsuchiya N, Sawada Y, Endo I, Nakatsura T

Cancer immunotherapy-targeted glypican-3 or neoantigens.

2018年03月 | Cancer science 109 3 531-541 

学術論文

Akazawa Y, Suzuki T, Nakatsura T

[Enhancement of Cytotoxic T Lymphocytes(CTLs)Infiltration into the Cancer Tissues].

2018年02月 | Gan to kagaku ryoho. Cancer & chemotherapy 45 2 227-231 

学術論文

清水康弘, 鈴木利宙, 遠藤格, 中面哲也

がん免疫療法の歴史と今後の課題

2018年 | 最新医学 73 2 174-181 

学術論文

Keisuke Tanamachi, Keisuke Nishino, Natsuki Mori, Toshihiro Suzuki, Sei-ichi Tanuma, Ryo Abe, Mitsutoshi Tsukimoto

Radiosensitizing Effect of P2X7 Receptor Antagonist on Melanoma in Vitro and in Vivo

2017年06月 | PHARMACEUTICAL SOC JAPAN BIOLOGICAL & PHARMACEUTICAL BULLETIN 40 6 878-887 

学術論文

鈴木 利宙, 中面 哲也

「特集」躍進するがん免疫療法 ネオアンチゲンとそれを標的としたがんワクチン療法

2017年 | 日本薬学会会誌「ファルマシア」 53 1 15-19 

学術論文

鈴木利宙, 安部良

IL-7の抗腫瘍応答における功罪 –抗腫瘍免疫応答の増強による抗腫瘍効果と炎症誘導を介した腫瘍形成の促進-

2017年 | 医学のあゆみ 261 11 1095-1101 

学術論文

Toshihiro Suzuki, Hidehiro Kishimoto, Ryo Abe

Requirement of interleukin 7 signaling for anti-tumor immune response under lymphopenic conditions in a murine lung carcinoma model

2016年03月 | SPRINGER CANCER IMMUNOLOGY IMMUNOTHERAPY 65 3 341-354 

学術論文

Hiromasa Okano, Tomoki Konishi, Toshihiro Suzuki, Takahiro Suzuki, Shinya Ariyasu, Shin Aoki, Ryo Abe, Masanori Hayase

Enrichment of circulating tumor cells in tumor-bearing mouse blood by a deterministic lateral displacement microfluidic device

2015年06月 | SPRINGER BIOMEDICAL MICRODEVICES 17 3 9964 

学術論文

Yosuke Hisamatsu, Ai Shibuya, Nozomi Suzuki, Toshihiro Suzuki, Ryo Abe, Shin Aoki

Design and Synthesis of Amphiphilic and Luminescent Tris-Cyclometalated Iridium(III) Complexes Containing Cationic Peptides as Inducers and Detectors of Cell Death via a Calcium-Dependent Pathway

2015年05月 | AMER CHEMICAL SOC BIOCONJUGATE CHEMISTRY 26 5 857-879 

学術論文

Highly robust protein production by co-cultureof CHO spheroids layered on feeder cells in serum-free medium.

2014年 | Colloid Polym. Sci. 292 4 839-844 

学術論文

Koichi Kutsuzawa, Chihiro Takahashi, Ryohei Sato, Toshihiro Suzuki, Hidehiro Kishimoto, Akiichi Murakami, Takachika Azuma, Ryo Abe, Hidenori Otsuka

Multiarray Formation of CHO Spheroids Cocultured with Feeder Cells for Highly Efficient Protein Production in Serum-Free Medium

2013年01月 | AMER SCIENTIFIC PUBLISHERS JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 13 1 229-235 

学術論文

Transient lymphopenia breaks costimulatory blockade-based peripheral tolerance and initiates cardiac allograft rejection

2013年 | A. J. Transplantation 20 1-12 

学術論文

Shinsuke Moromizato, Yosuke Hisamatsu, Toshihiro Suzuki, Yasuki Matsuo, Ryo Abe, Shin Aoki

Design and Synthesis of a Luminescent Cyclometalated Iridium(III) Complex Having N,N-Diethylamino Group that Stains Acidic Intracellular Organelles and Induces Cell Death by Photoirradiation

2012年12月 | AMER CHEMICAL SOC INORGANIC CHEMISTRY 51 23 12697-12706 

学術論文

Shinya Ariyasu, Kengo Hanaya, Eita Watanabe, Toshihiro Suzuki, Kazutaka Horie, Masanori Hayase, Ryo Abe, Shin Aoki

Selective Capture and Collection of Live Target Cells Using a Photoreactive Silicon Wafer Device Modified with Antibodies via a Photocleavable Linker

2012年09月 | AMER CHEMICAL SOC LANGMUIR 28 36 13118-13126 

学術論文

Shoichi Iida, Kazuya Omoto, Izumi Kanemitsu, Kiyoshi Setoguchi, Hideki Ishida, Kazunari Tanabe, Toshihiro Suzuki, Yasuyuki Tashiro, Hidehiro Kishimoto, Ryo Abe

Interleukin-6 Receptor Signaling Disruption Prevents Cardiac Allograft Deterioration in Mice

2012年08月 | BASKENT UNIV EXPERIMENTAL AND CLINICAL TRANSPLANTATION 10 4 375-385 

学術論文

Masanori Kitamura, Toshihiro Suzuki, Ryo Abe, Takeru Ueno, Shin Aoki

B-11 NMR Sensing of d-Block Metal Ions in Vitro and in Cells Based on the Carbon-Boron Bond Cleavage of Phenylboronic Acid-Pendant Cyclen (Cyclen=1,4,7,10-Tetraazacyclododecane)

2011年11月 | AMER CHEMICAL SOC INORGANIC CHEMISTRY 50 22 11568-11580 

学術論文

Tomoyoshi Yamano, Sho Watanabe, Hiroyuki Hasegawa, Toshihiro Suzuki, Ryo Abe, Hideaki Tahara, Takeshi Nitta, Naozumi Ishimaru, Jonathan Sprent, Hidehiro Kishimoto

Ex vivo-expanded DCs induce donor-specific central and peripheral tolerance and prolong the acceptance of donor skin grafts

2011年03月 | AMER SOC HEMATOLOGY BLOOD 117 9 2640-2648 

学術論文

Kiyoshi Setoguchi, Hidehiro Kishimoto, Sakiko Kobayashi, Hiroaki Shimmura, Hideki Ishida, Daisuke Toki, Toshihiro Suzuki, Kazunobu Ohnuki, Yoshiki Tate, Shigeru Fujioka, Ryo Abe, Kazunari Tanabe

Potential role of host effector memory CD8(+) T cells in marrow rejection after mixed chimerism induction in cynomolgus monkeys

2010年08月 | ELSEVIER SCIENCE BV TRANSPLANT IMMUNOLOGY 23 4 194-203 

学術論文

Saito T, Takayama T, Osaki T, Nagai S, Suzuki T, Sato M, Kuwano H, Tahara H

Combined mobilization and stimulation of tumor-infiltrating dendritic cells and natural killer cells with Flt3 ligand and IL-18 in vivo induces systemic antitumor immunity.

2008年10月 | Cancer science 99 10 2028-2036 

学術論文

鈴木 利宙

Homeostatic Proliferationに伴う抗腫瘍効果誘導におけるCD28シグナルの役割

2008年07月 | 東京大学 124042 

学術論文

Suzuki T, Ogawa S, Tanabe K, Tahara H, Abe R, Kishimoto H

Induction of antitumor immune response by homeostatic proliferation and CD28 signaling.

2008年04月 | Journal of immunology 180 7 4596-4605 

学術論文

M Sato, T Takayama, H Tanaka, J Konishi, T Suzuki, T Kaiga, H Tahara

Generation of mature dendritic cells fully capable of T helper type 1 polarization using OK-432 combined with prostaglandin E-2

2003年12月 | JAPANESE CANCER ASSOC CANCER SCIENCE 94 12 1091-1098 

学術論文

T Shimizu, K Sato, T Suzuki, K Tachibana, K Takeda

Induction of plasminogen activator inhibitor-2 is associated with suppression of invasive activity in TPA-mediated differentiation of human prostate cancer cells

2003年09月 | ACADEMIC PRESS INC ELSEVIER SCIENCE BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 309 2 267-271 

学術論文

T Suzuki, T Shimizu, K Satoh, R Sugibayashi, K Takeda

Differential expression of genes during TPA-induced differentiation of human prostatic cancer TSU-Pr1 cells

2002年12月 | PROFESSOR D A SPANDIDOS INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 10 6 735-739 

学術論文

R Sugibayashi, Y Kiguchi, T Shimizu, T Suzuki, H Hamada, K Takeda

Up-regulation of p21(WAF1/CIP1) levels leads to growth suppression of prostate cancer cell lines

2002年03月 | INT INST ANTICANCER RESEARCH ANTICANCER RESEARCH 22 2A 713-719 

学術論文

Up-regulation of p21(WAF1/CIP1) leads to morphologic changes and esterase activity in TPA-mediated differentiation of human prostate cancer cell line TSU-Pr1.

2001年03月 | Oncogene 20 10 1220-1228