Nanobiotechnology of Biomacromolecules |
NISHIDA, Hirokazu |
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【Biosciences･2nd semester】
14-1-0415 |
| １． |
Objectives |
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The main purpose of this class is to study nanobiotechnology mainly from the viewpoint of the structural research of biomacromolecules, by briefly understanding the methodologies of structural analyses of proteins and nucleic acids with a focus on X-ray crystallography. Additionally, how to make use of biomacromolecules such as enzymes by their mutations on the basis of the structural insights of the molecules will be explained.
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Outline |
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The reason why the enzyme molecules are folded in each unique three-dimensional structure and the structure-function relationship of these molecules will be illustrated in detail by examples. How to utilize the structural information on biomacromolecules for industrial use will be discussed. Especially about some DNA transaction enzymes, the constructions of the mutants effective for industrial usages will be detailed.
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