| １． |
Outline |
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The knowledge of organic chemistry is essential to study a variety of fields in bioscience. All the reactions occurring in our body has nothing to surprise, they just obey the laws of organic chemistry, which means that they are the same reactions occurring in glass flasks. To understand how the life is maintained and to develop novel drags, the knowledge of organic chemistry is needed. The aim of this course is to help students acquire fundamentals of organic chemistry.
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| ２． |
Objectives |
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The goals of this course are to be understand the followings:
(1) Properties of aromatic compounds
(2) Organohalogen compounds
(3) Oxygen containing compounds
(4) The mechanism of electrophilic substitution on aromatic compounds
(5) The mechanism of nucleophilic subsdutitution reactions
(6) The mechanism of elimination reactions
(7) Basic properties of organimetalic compounds
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| ３． |
Grading Policy |
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Grading will be decided based on term-end examination.
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| ４． |
Textbook and Reference |
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“Organic Chemistry: A short course” 3rd. Ed. H Hart, L. Craine, D. Hart. (in Japanese) (ISBN4-563-04587-X).
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| ５． |
Requirements (Assignments) |
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Students should review the courses of “Chemistry 1”, “Chemistry 2” and “Fundamentals of Organic Chemistry”. An exercises sheet to be solved will be given after the class. Students will submit it before the next class.
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| ６． |
Note |
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Nothing special.
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| ７． |
Schedule |
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１. Aromatic compounds 1: Nomenclature, Aromaticity
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２. Aromatic compounds 2: Electrophylic Substitution, nitrations, haloganations, etc
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３. Aromatic compounds 3: Electrophylic Substitution, Reaction mechanism
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４. Aromatic compounds 4: o,p-orientation, m-orientation
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５. Organohalogen compounds 1: Nomencleature, inductive effect
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６. Organohalogen compounds 2: SN1 ans SN2 reactions
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７. Organohalogen compounds 3: E1 and E2 reactions
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８. Oxygen containing compounds 1: Nomencleature and reactivity of Alcohols
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９. Oxygen containing compounds 2: Synthesisi and reaction of Alcohols
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10. Oxygen containing compounds 3: Phenols and Thiols
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11. Oxygen containing compounds 4: Nomencleature and reactivits of Ethers and Epoxides
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12. Oxygen containing compounds 5: Synthesys of Ethers and Epoxides
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13. Oxygen containing compounds 6: Reactions of Ethers and Epoxides
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14. Organometalic compounds: Grignard reagents and organolithium compounds
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15. Summary and Examination
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|
| １． |
Outline |
|
The knowledge of organic chemistry is essential to study a variety of fields in bioscience. All the reactions occurring in our body has nothing to surprise, they just obey the laws of organic chemistry, which means that they are the same reactions occurring in glass flasks. To understand how the life is maintained and to develop novel drags, the knowledge of organic chemistry is needed. The aim of this course is to help students acquire fundamentals of organic chemistry.
|
| ２． |
Objectives |
|
The goals of this course are to be understand the followings:
(1) Properties of aromatic compounds
(2) Organohalogen compounds
(3) Oxygen containing compounds
(4) The mechanism of electrophilic substitution on aromatic compounds
(5) The mechanism of nucleophilic subsdutitution reactions
(6) The mechanism of elimination reactions
(7) Basic properties of organimetalic compounds
|
| ３． |
Grading Policy |
|
Grading will be decided based on term-end examination.
|
| ４． |
Textbook and Reference |
|
“Organic Chemistry: A short course” 3rd. Ed. H Hart, L. Craine, D. Hart. (in Japanese) (ISBN4-563-04587-X).
|
| ５． |
Requirements (Assignments) |
|
Students should review the courses of “Chemistry 1”, “Chemistry 2” and “Fundamentals of Organic Chemistry”. An exercises sheet to be solved will be given after the class. Students will submit it before the next class.
|
| ６． |
Note |
|
Nothing special.
|
| ７． |
Schedule |
|
１. Aromatic compounds 1: Nomenclature, Aromaticity
|
２. Aromatic compounds 2: Electrophylic Substitution, nitrations, haloganations, etc
|
３. Aromatic compounds 3: Electrophylic Substitution, Reaction mechanism
|
４. Aromatic compounds 4: o,p-orientation, m-orientation
|
５. Organohalogen compounds 1: Nomencleature, inductive effect
|
６. Organohalogen compounds 2: SN1 ans SN2 reactions
|
７. Organohalogen compounds 3: E1 and E2 reactions
|
８. Oxygen containing compounds 1: Nomencleature and reactivity of Alcohols
|
９. Oxygen containing compounds 2: Synthesisi and reaction of Alcohols
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10. Oxygen containing compounds 3: Phenols and Thiols
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11. Oxygen containing compounds 4: Nomencleature and reactivits of Ethers and Epoxides
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12. Oxygen containing compounds 5: Synthesys of Ethers and Epoxides
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13. Oxygen containing compounds 6: Reactions of Ethers and Epoxides
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14. Organometalic compounds: Grignard reagents and organolithium compounds
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15. Summary and Examination
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