Cell Biology

UCHINO, Shigeo
  Elective Requisites  2 credits
【Biosciences・2nd semester】
19-1-0367-3732

1.
Outline
Students will study the structure and the physiological properties of cells, including the function of organelles, the mechanisms of cell cycle, division and death. Since the lecture includes the practice session, students will confirm their own degrees of understanding. In this lecture, students will acquire knowledge and train comprehensive thinking skill on DP1 and DP2.

2.
Objectives
Cell biology is the study of biological processes within living organisms. The research area of cell biology is closely related to genetics, biochemistry, molecular biology, immunology, and neuroscience. The goal of this lecture is to understand the structure and function of cells that constitute living organisms. Students can describe the technical terms learned in each lecture. In addition, they can combine their knowledge and solve the exercises given in each lecture.
3.
Grading Policy
Evaluation is conducted on regular examination results. A score of 60% or more is passed. Regular examination can be taken regardless of attendance rate, but students with attendance rates of less than 60% (less than 9 courses) will not qualify for re-examination. After the examination, I will explain some of its contents.

4.
Textbook and Reference
Textbook:『基礎から学ぶ生物学・細胞生物学(第3版)』和田勝著(羊土社(ISBN 978-4-7581-2065-4))
Distribute the print if necessary. After each lecture, the contents of the lecture will be posted on the LMS.
Reference book:『理系総合のための生命科学(第4版)』東京大学生命科学教科書編集委員会篇(羊土社)(ISBN 978-4-7581-2086-9)

5.
Requirements (Assignments)
Review in advance the "Biology" learned in high school and the first year of university. For each lecture, read in advance the textbook page shown in each of the following times. About 1 hour as preparatory learning. Please read the textbooks for the next lecture, and note what you understood and did not understand. About 1 hour as review. Review the lecture that you did not understand, especially in the pre-study, and put in a note whether you understood. Review the exercises (listed in LMS) conducted during the lecture. The point that the student did not understand is that the student need to read the textbook again, review the contents of the lecture in LMS, ask the teacher questions, and so on.

6.
Note
I strongly recommend to take this course for students who wish to take "Experiments in Animal Physiology"
7.
Schedule
1. Introduction to Cell Biology: Review of Biology
Textbook: Introduction (P18-22), Chapter 1. Basics of Biology (P31-32)

2. Cell Structure 1: Cell membranes and Cellular organelles
Textbook: Chapter 2. Profile of cells (P48-53, P63-71)

3. Cell Structure 2: Cytoskeleton and Cell movement
Textbook: Chapter 5. Proteins are responsible for various cellular activities (P131-139)

4. Expression of gene 1: Structure and Replication of gene
Textbook: Chapter 7. The road to multicellular organisms 2 (P 169-175)

5. Expression of gene 2: Transcription and Translation
Textbook: Chapter 3. What determines cell shape and function (P 76-93)

6. Exercise and Summary:
Review the contents of the first to fifth lectures while solving the exercises.

7. Cell Function 1: Cell cycle and Cell division
Textbook: Chapter 7. The road to multicellular organisms 2 (P175-177)
Chapter 8. The road to multicellular organism 3 (P 185-189)

8. Cell Function 2: Cell death and Regeneration
Textbook: Chapter 10. Living and dying (P246-254)

9. Cell Function 3: Energy production and Metabolism
Textbook: Chapter 4. For living and active cells (P102-113)

10. Exercise and Summary:
Review the contents of the first to ninth lectures while solving the exercises.

11. Principles and Diversity of Signal transduction
Textbook: Chapter 6. The road to multicellular organisms 1 (P 147-154)
Chapter 11. Organized as an individual (P 284-288)

12. Immunology
Textbook: Chapter 9. The immune system to protect individuals (P213-234)

13. Neurology
Textbook: Chapter 11. Organized as an individual (P271-276)

14. Cell Biology and Life sciences:
Introduces the latest topics in cell biology. Example: Disease model mouse produced by using gene modification technology and regenerative medicine.

15. Examination and Commentary:
I will give examination and explain some of its contents.

1.
Outline
Students will study the structure and the physiological properties of cells, including the function of organelles, the mechanisms of cell cycle, division and death. Since the lecture includes the practice session, students will confirm their own degrees of understanding. In this lecture, students will acquire knowledge and train comprehensive thinking skill on DP1 and DP2.

2.
Objectives
Cell biology is the study of biological processes within living organisms. The research area of cell biology is closely related to genetics, biochemistry, molecular biology, immunology, and neuroscience. The goal of this lecture is to understand the structure and function of cells that constitute living organisms. Students can describe the technical terms learned in each lecture. In addition, they can combine their knowledge and solve the exercises given in each lecture.
3.
Grading Policy
Evaluation is conducted on regular examination results. A score of 60% or more is passed. Regular examination can be taken regardless of attendance rate, but students with attendance rates of less than 60% (less than 9 courses) will not qualify for re-examination. After the examination, I will explain some of its contents.

4.
Textbook and Reference
Textbook:『基礎から学ぶ生物学・細胞生物学(第3版)』和田勝著(羊土社(ISBN 978-4-7581-2065-4))
Distribute the print if necessary. After each lecture, the contents of the lecture will be posted on the LMS.
Reference book:『理系総合のための生命科学(第4版)』東京大学生命科学教科書編集委員会篇(羊土社)(ISBN 978-4-7581-2086-9)

5.
Requirements (Assignments)
Review in advance the "Biology" learned in high school and the first year of university. For each lecture, read in advance the textbook page shown in each of the following times. About 1 hour as preparatory learning. Please read the textbooks for the next lecture, and note what you understood and did not understand. About 1 hour as review. Review the lecture that you did not understand, especially in the pre-study, and put in a note whether you understood. Review the exercises (listed in LMS) conducted during the lecture. The point that the student did not understand is that the student need to read the textbook again, review the contents of the lecture in LMS, ask the teacher questions, and so on.

6.
Note
I strongly recommend to take this course for students who wish to take "Experiments in Animal Physiology"
7.
Schedule
1. Introduction to Cell Biology: Review of Biology
Textbook: Introduction (P18-22), Chapter 1. Basics of Biology (P31-32)

2. Cell Structure 1: Cell membranes and Cellular organelles
Textbook: Chapter 2. Profile of cells (P48-53, P63-71)

3. Cell Structure 2: Cytoskeleton and Cell movement
Textbook: Chapter 5. Proteins are responsible for various cellular activities (P131-139)

4. Expression of gene 1: Structure and Replication of gene
Textbook: Chapter 7. The road to multicellular organisms 2 (P 169-175)

5. Expression of gene 2: Transcription and Translation
Textbook: Chapter 3. What determines cell shape and function (P 76-93)

6. Exercise and Summary:
Review the contents of the first to fifth lectures while solving the exercises.

7. Cell Function 1: Cell cycle and Cell division
Textbook: Chapter 7. The road to multicellular organisms 2 (P175-177)
Chapter 8. The road to multicellular organism 3 (P 185-189)

8. Cell Function 2: Cell death and Regeneration
Textbook: Chapter 10. Living and dying (P246-254)

9. Cell Function 3: Energy production and Metabolism
Textbook: Chapter 4. For living and active cells (P102-113)

10. Exercise and Summary:
Review the contents of the first to ninth lectures while solving the exercises.

11. Principles and Diversity of Signal transduction
Textbook: Chapter 6. The road to multicellular organisms 1 (P 147-154)
Chapter 11. Organized as an individual (P 284-288)

12. Immunology
Textbook: Chapter 9. The immune system to protect individuals (P213-234)

13. Neurology
Textbook: Chapter 11. Organized as an individual (P271-276)

14. Cell Biology and Life sciences:
Introduces the latest topics in cell biology. Example: Disease model mouse produced by using gene modification technology and regenerative medicine.

15. Examination and Commentary:
I will give examination and explain some of its contents.