Molecular Genetics

MIYAMOTO. Koji
  Elective  2 credits
【Biosciences・1st semester】
19-1-0368-4946

1.
Outline
The purpose of this course is to learn the following.
 (1) The structures of DNA and RNA
 (2) Replication of DNA
 (3) Gene expression and its regulation
2.
Objectives
This course aims to understand the molecular mechanisms by which the genome is maintained and the genes are expressed or regulated.
3.
Grading Policy
Final grade will be calculated according to the midterm examination (33%) and the final examination (67%). To pass, students must earn at least 60 points out of 100.
4.
Textbook and Reference
Textbook: Text book for biology in a university. Vol. 2 "Molecular genetics" (in Japanese), David Sadave et al., Kodansha Ltd., ISBN:978-4-06-257673-4
5.
Requirements (Assignments)
Students have to prepare each lecture by reading the corresponding chapter in the textbook and summarizing the content of next lecture in a notebook. This preparation will take one hour.
There will be homework each week. Students should review the questions they did not understand in their homework. This review will take two hours.
6.
Note
Students should take "Fundemental genetics". Please review the contents of "Fundemental genetics". Handout will be posted on LMS.
7.
Schedule
1. Cell cylcle and cell division
2. Chromosome distribution
3. Mendelian inheritance
4. Mendelian inheritance and non Mendelian inheritance
5. Genetic linkage and recombination
6. Structure of DNA
7. Replication of DNA
8. Midterm examination and commentary
9. Transcription
10. Translation, protein modification and mutation
11. DNA replication and gene expression in virus
12. Genetics in Prokaryote
13. Gene expression in Prokaryote
14. Genome and gene expression in Eukaryote
15. Final examination and commentary
1.
Outline
The purpose of this course is to learn the following.
 (1) The structures of DNA and RNA
 (2) Replication of DNA
 (3) Gene expression and its regulation
2.
Objectives
This course aims to understand the molecular mechanisms by which the genome is maintained and the genes are expressed or regulated.
3.
Grading Policy
Final grade will be calculated according to the midterm examination (33%) and the final examination (67%). To pass, students must earn at least 60 points out of 100.
4.
Textbook and Reference
Textbook: Text book for biology in a university. Vol. 2 "Molecular genetics" (in Japanese), David Sadave et al., Kodansha Ltd., ISBN:978-4-06-257673-4
5.
Requirements (Assignments)
Students have to prepare each lecture by reading the corresponding chapter in the textbook and summarizing the content of next lecture in a notebook. This preparation will take one hour.
There will be homework each week. Students should review the questions they did not understand in their homework. This review will take two hours.
6.
Note
Students should take "Fundemental genetics". Please review the contents of "Fundemental genetics". Handout will be posted on LMS.
7.
Schedule
1. Cell cylcle and cell division
2. Chromosome distribution
3. Mendelian inheritance
4. Mendelian inheritance and non Mendelian inheritance
5. Genetic linkage and recombination
6. Structure of DNA
7. Replication of DNA
8. Midterm examination and commentary
9. Transcription
10. Translation, protein modification and mutation
11. DNA replication and gene expression in virus
12. Genetics in Prokaryote
13. Gene expression in Prokaryote
14. Genome and gene expression in Eukaryote
15. Final examination and commentary