| １． |
Outline |
|
Students will study the mechanisms of gene expression, protein synthesis, and signal transduction including enzymology within living organisms. Since the lecture includes the practice session, students will confirm their own degrees of understanding. In this lecture, students will acquire knowledge and train comprehensive thinking skill on DP1 and DP2.
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| ２． |
Objectives |
|
Biochemistry is the study of chemical and biological processes within living organisms. The goal of this lecture is to understand the structure and function of the organic chemicals that constitute living organisms. Students can describe the technical terms learned in each lecture. In addition, they can combine their knowledge and solve the exercises given in each lecture.
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| ３． |
Grading Policy |
|
Evaluation is conducted on regular examination results. A score of 60% or more is passed. Regular examination can be taken regardless of attendance rate, but students with attendance rates of less than 60% (less than 9 courses) will not qualify for re-examination. After the examination, I will explain some of its contents.
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| ４． |
Textbook and Reference |
|
Textbook：『基礎からしっかり学ぶ生化学』山口雄輝編著、成田央著（羊土社）（ISBN 978-4-7581-2050-0）
Distribute the print if necessary. After each lecture, the contents of the lecture will be posted on the LMS.
Reference book：『理系総合のための生命科学（第４版）』東京大学生命科学教科書編集委員会篇（羊土社）（ISBN 978-4-7581-2086-9）
|
| ５． |
Requirements (Assignments) |
|
Review in advance the "Biology" "Cell biology" learned in the first year of university. For each lecture, read in advance the textbook page shown in each of the following times. About 1 hour as preparatory learning. Please read the textbooks for the next lecture, and note what you understood and did not understand. About 1 hour as review. Review the lecture that you did not understand, especially in the pre-study, and put in a note whether you understood. Review the exercises (listed in LMS) conducted during the lecture. The point that the student did not understand is that the student need to read the textbook again, review the contents of the lecture in LMS, ask the teacher questions, and so on.
|
| ６． |
Note |
|
|
| ７． |
Schedule |
|
１. Introduction to Biochemistry: Energy metabolism and Cell biology
Textbook: Chapter 5. Glucose metabolism 1 (P90-98), Chapter 6. Glucose metabolism 2 (P109-123)
|
２. Expression of gene 1: Structure and Synthesis of nucleic acid
Textbook: Chapter 2. Structure and Function of nucleic acid (P 43-57)
|
３. Expression of gene 2: Replication of gene
Textbook: Chapter 10. DNA Replication, Repair, Recombination (P171-186)
|
４. Expression of gene 3: Transcription of gene
Textbook: Chapter 11. Transcription and RNA processing (P187-202)
|
５. Protein: Synthesis and Higher structure of protein
Textbook: Chapter 1. Structure and Function of protein (P23-35)
Chapter 12. Translation and Post-translational Modification (P206-214)
|
６. Exercise and Summary:
Review the contents of the first to fifth lectures while solving the exercises.
|
７. Signal Transduction 1: Receptor
Textbook: Chapter 3. Monosaccharides and polysaccharides, lipids and cell membranes (P70-75), Chapter 12. Translation and Post-translational Modification (P217-223)
|
８. Signal Transduction 2: Classification and Function of enzyme
Textbook: Chapter 4. Kinetics of Enzyme Reaction (P 76-83)
|
９. Signal Transduction 3: Mechanism of enzyme reaction and Regulation of enzyme activity
Textbook: Chapter 4. Kinetics of Enzyme Reaction (P 83-88)
|
10. Exercise and Summary:
Review the contents of the first to ninth lectures while solving the exercises.
|
11. Biochemistry of metabolism 1: Signal transduction and Cellular responses
Textbook: Chapter 13. Signal Transduction (P224-235)
|
12. Biochemistry of metabolism 2: Hormones and Bioregulation
I will give lectures focusing on printing. Regulation mechanism of blood glucose concentration, etc.
|
13. Biochemistry of metabolism 3: Metabolic abnormalities, diseases
I will give lectures focusing on printing. Such as autophagy, epigenetics and developmental disorders.
|
14. Biochemistry and Life sciences: Technology of Genetic engineering, Cell engineering, Chromosome engineering
Introduce the important topics of PCR and electrophoresis, gene recombination, and application examples of gene modification technology.
|
15. Examination and Commentary:
I will give examination and explain some of its contents.
|
|
| １． |
Outline |
|
Students will study the mechanisms of gene expression, protein synthesis, and signal transduction including enzymology within living organisms. Since the lecture includes the practice session, students will confirm their own degrees of understanding. In this lecture, students will acquire knowledge and train comprehensive thinking skill on DP1 and DP2.
|
| ２． |
Objectives |
|
Biochemistry is the study of chemical and biological processes within living organisms. The goal of this lecture is to understand the structure and function of the organic chemicals that constitute living organisms. Students can describe the technical terms learned in each lecture. In addition, they can combine their knowledge and solve the exercises given in each lecture.
|
| ３． |
Grading Policy |
|
Evaluation is conducted on regular examination results. A score of 60% or more is passed. Regular examination can be taken regardless of attendance rate, but students with attendance rates of less than 60% (less than 9 courses) will not qualify for re-examination. After the examination, I will explain some of its contents.
|
| ４． |
Textbook and Reference |
|
Textbook：『基礎からしっかり学ぶ生化学』山口雄輝編著、成田央著（羊土社）（ISBN 978-4-7581-2050-0）
Distribute the print if necessary. After each lecture, the contents of the lecture will be posted on the LMS.
Reference book：『理系総合のための生命科学（第４版）』東京大学生命科学教科書編集委員会篇（羊土社）（ISBN 978-4-7581-2086-9）
|
| ５． |
Requirements (Assignments) |
|
Review in advance the "Biology" "Cell biology" learned in the first year of university. For each lecture, read in advance the textbook page shown in each of the following times. About 1 hour as preparatory learning. Please read the textbooks for the next lecture, and note what you understood and did not understand. About 1 hour as review. Review the lecture that you did not understand, especially in the pre-study, and put in a note whether you understood. Review the exercises (listed in LMS) conducted during the lecture. The point that the student did not understand is that the student need to read the textbook again, review the contents of the lecture in LMS, ask the teacher questions, and so on.
|
| ６． |
Note |
|
|
| ７． |
Schedule |
|
１. Introduction to Biochemistry: Energy metabolism and Cell biology
Textbook: Chapter 5. Glucose metabolism 1 (P90-98), Chapter 6. Glucose metabolism 2 (P109-123)
|
２. Expression of gene 1: Structure and Synthesis of nucleic acid
Textbook: Chapter 2. Structure and Function of nucleic acid (P 43-57)
|
３. Expression of gene 2: Replication of gene
Textbook: Chapter 10. DNA Replication, Repair, Recombination (P171-186)
|
４. Expression of gene 3: Transcription of gene
Textbook: Chapter 11. Transcription and RNA processing (P187-202)
|
５. Protein: Synthesis and Higher structure of protein
Textbook: Chapter 1. Structure and Function of protein (P23-35)
Chapter 12. Translation and Post-translational Modification (P206-214)
|
６. Exercise and Summary:
Review the contents of the first to fifth lectures while solving the exercises.
|
７. Signal Transduction 1: Receptor
Textbook: Chapter 3. Monosaccharides and polysaccharides, lipids and cell membranes (P70-75), Chapter 12. Translation and Post-translational Modification (P217-223)
|
８. Signal Transduction 2: Classification and Function of enzyme
Textbook: Chapter 4. Kinetics of Enzyme Reaction (P 76-83)
|
９. Signal Transduction 3: Mechanism of enzyme reaction and Regulation of enzyme activity
Textbook: Chapter 4. Kinetics of Enzyme Reaction (P 83-88)
|
10. Exercise and Summary:
Review the contents of the first to ninth lectures while solving the exercises.
|
11. Biochemistry of metabolism 1: Signal transduction and Cellular responses
Textbook: Chapter 13. Signal Transduction (P224-235)
|
12. Biochemistry of metabolism 2: Hormones and Bioregulation
I will give lectures focusing on printing. Regulation mechanism of blood glucose concentration, etc.
|
13. Biochemistry of metabolism 3: Metabolic abnormalities, diseases
I will give lectures focusing on printing. Such as autophagy, epigenetics and developmental disorders.
|
14. Biochemistry and Life sciences: Technology of Genetic engineering, Cell engineering, Chromosome engineering
Introduce the important topics of PCR and electrophoresis, gene recombination, and application examples of gene modification technology.
|
15. Examination and Commentary:
I will give examination and explain some of its contents.
|
|
|