Basic Bioinformatics

ASAHINA, Masashi
  Elective  2 credits
【Biosciences・1st semester】
19-1-0398-2639

1.
Outline
This class will provide an essential background on bioinformatics, basic techniques for database and/or web-tool analysis, using PubMed, CLUSTALW, BLAST, PSORT, SOSUI, KEGG, and GO, etc.
Covered topics include databases of life science journals, sequence, structure and function databases of DNA and protein molecules, advanced sequence and structure alignment methods, database of functions and utilities of the biological system, and Gene ontology.
2.
Objectives
This is a hands-on, project-oriented class.
The aims of this course are to gain essential background on bioinformatics and basic techniques to identify, obtain, and analyze research information on molecular biology by using Internet tools.
3.
Grading Policy
Progress report and Take-home Examination(50%), Practical Test(50%).
4.
Textbook and Reference
A Handout and resources will be provided throughout the course using LMS.
5.
Requirements (Assignments)
This class will be held based on essential background of Molecular Biology.
Students must be familiar with basic computer operations.
The Handout and the Slides will be copied to LMS.
Read materials and references before and after the class.

6.
Note
To Be Announced.

7.
Schedule
1. Introduction
2. CiNii, IPDL
3. PubMed
4. NCBI,DDBJ
5. CLUSTALW,TreeView
6. BLAST
7. BLASTN
8. BLASTP
9. BLASTX,TBLASTN
10. PSI-BLAST,PHI-BLAST
11. PSORT,SOSUI,TMHMM
12. GO,GEO,KEGG
13. Gene Ontology
14. Entrez、GenomeNET, etc.
15. Final Exam and its review in practice
1.
Outline
This class will provide an essential background on bioinformatics, basic techniques for database and/or web-tool analysis, using PubMed, CLUSTALW, BLAST, PSORT, SOSUI, KEGG, and GO, etc.
Covered topics include databases of life science journals, sequence, structure and function databases of DNA and protein molecules, advanced sequence and structure alignment methods, database of functions and utilities of the biological system, and Gene ontology.
2.
Objectives
This is a hands-on, project-oriented class.
The aims of this course are to gain essential background on bioinformatics and basic techniques to identify, obtain, and analyze research information on molecular biology by using Internet tools.
3.
Grading Policy
Progress report and Take-home Examination(50%), Practical Test(50%).
4.
Textbook and Reference
A Handout and resources will be provided throughout the course using LMS.
5.
Requirements (Assignments)
This class will be held based on essential background of Molecular Biology.
Students must be familiar with basic computer operations.
The Handout and the Slides will be copied to LMS.
Read materials and references before and after the class.

6.
Note
To Be Announced.

7.
Schedule
1. Introduction
2. CiNii, IPDL
3. PubMed
4. NCBI,DDBJ
5. CLUSTALW,TreeView
6. BLAST
7. BLASTN
8. BLASTP
9. BLASTX,TBLASTN
10. PSI-BLAST,PHI-BLAST
11. PSORT,SOSUI,TMHMM
12. GO,GEO,KEGG
13. Gene Ontology
14. Entrez、GenomeNET, etc.
15. Final Exam and its review in practice