Microbial Chemistry
TeachersTAKAHASHI, SenjiStaffInfo
Grade, SemesterYear 3 1st semest [Department of Biosciences, Faculty of Science and Engineering]
CategorySpecial Subjects
Elective, CreditsElective 2credit
 Syllabus Number5L363

Course Description

After reviewing the basic knowledge of microbiology, this course covers the basic and topics of pathogenic microorganisms, prevention of infection by them, and chemical therapy using the supplementary materials provided.
The following subjects will be studied during the course.
(1) taxonomy and identification of microorganisms
(2) infection and defense
(3) pathogenic microorganisms
(4) antimicrobial chemotherapy

Course Objectives

Microorganisms are utilizable in our personal lives and are used in industry. A large number of valuable antibiotics have been isolated from natural resources so far and used as drugs. This course will provide background knowledge of how antibiotics have been discovered from natural resources and an explanation of why antibiotics exist in nature.

Grading Policy

Reports and occasional test (20%) results are considered with final examination results (80%).

Textbook and Reference

TextbookTeaching material (prints) will be distributed.
References"Kagakuryouhougaku" Yoshio Ueno and Satoshi Omura (in Japanese)Nankoudo


(Preparation of lecture) The students are required to read the coresponding part of the text in advance, make it clear what they don't understand, and be ready to ask during the lecture (2 hr.).
(Review of lecture) The stydents should check any contents, whichi could not be understood, after the lecture (1 hr.).


It is strongly suggested for students to study "Fundamental Microbiology", "Fundamentals of Organic Chemistry" and "Organic Chemistry 1 and 2" beforehand in classes. Studying beforehand is strongly suggested because you will learn many chemical reactions in this class.


1Bacterial classification

2Bacterial morphology and cell structure

3Infection and defense (1) (Infection route and infection source)

4Infection and defense (2) (Opportunistic infection and microbial substitution)

5Pathogenic microorganisms (1) The gram-positive cocci

6Pathogenic microorganisms (2) The gram-positive bacilli

7Pathogenic microorganisms (3) The gram-negative cocci

8Pathogenic microorganisms (4) The gram-negative bacilli

9Pathogenic microorganisms (5) Spirochete, rickettsial and chlamydial pathogens

10Antimicrobial agents (1) Development history of antimicrobial agents and definition of antibiotics

11Antimicrobial agents (2) Application of microorganisms (Cultivation,taxonomy and identification)
12Cell wall synthesis inhibitor (1) Penicillins

13Cell wall synthesis inhibitor (2) Cephems

14Cell wall synthesis inhibitor (3) Carbapenems, oxapenems and monobactams

15Cell wall synthesis inhibitor (4) β-Lactamase inhibitors