Brain and Neuroscience
TeachersUCHINO, ShigeoStaffInfo
Grade, SemesterYear 1 2nd semest [Master's program, Division of Integrated Science and Engineering]
CategorySpecial Subjects
Elective, CreditsElective 2credit
 Syllabus Number

Course Description

Students will study the structure of brain, function of neuron and glial cells, which constitute a nervous system, including neural circuit based on synapses. Furthermore, the lecture will provide neuropathlogy of brain diseases and several current topics on neuroscience, including animal model for brain disease and regenerative medicine. In this lecture, students will acquire knowledge and train comprehensive thinking skill on DP1,DP2 and DP3.

Course Objectives

Neurobiology is the study of operating principles of nervous system. The goal of this lecture is to understand the structure of brain including neural circuit, higher brain function, and brain diseases such as neurodegenerative disease and developmental disorders. Students can understand technical terms, describe their contents, and verbally explain them. Students can understand abstracts and diagrams of the original English papers and explain them verbally.

Grading Policy

Evaluation is comprehensively conducted based on the presentation of the issues in the lecture (approximately 70%) and the issue report (approximately 30%). The report will be returned after scoring.

Textbook and Reference

坂井建雄、久光正監修成美堂出版(ISBN 978-4-415-30999-6)
References脳神経科学イラストレイテッド(第3版)真鍋俊也、森寿、渡辺雅彦、岡野栄之、宮川剛編集羊土社(ISBN 978-4-7581-2040-1)
References脳神経ペディア渡辺雅彦著羊土社(ISBN 978-4-7581-2082-1)


Since English original papers and reviews are used, you will need a dictionary.


Distribute the prints if necessary.


1Chapter 1. Introduction of neurobiology

2Chapter 2. Structure of brain 1: Basic structure of brain (cerebrum, cerebellum, hippocampus, striatum)
Textbook; P8-P13, P66-P67, P76-P79

3Chapter 3. Structure of brain 2: Neural cells(neurons and glial cells)
Textbook; P20-P21, P28-P29

4Chapter 4. Structure of brain 3: Structure and function of synapses
Textbook; P22-P27

5Chapter 5. Molecular mechanism of neuronal signal transduction: excitatory synapse and inhibitory synapse

6Chapter 6. Development of brain: Neuronal migration and laminar formation
Textbook; P16-P19, P30-P37

7Chapter 7. Molecular mechanism of neuronal maturation: Formation and pruning of synapses

8Chapter 8. Molecular mechanism of neuronal plasticity: Role of synaptic molecules
Textbook; P110-P123

9Chapter 9. Higher brain function 1: Recognition, perception, learning and memory
Textbook; P110-P123

10Chapter 10. Higher brain function 2: Esthesiohysiology in brain
Textbook; P90-P107

11Chapter 11. Higher brain function 3: Exercise physiology in brain
Textbook; P46-P51, P80-P89

12Chapter 12. Higher brain function 4: Mental biology in brain
Textbook; P124-P133

13Chapter 13. Brain disease 1: Neurodegenerative disease and cerebrovascular disease
Textbook; P146-P155

14Chapter 14. Brain disease 2: Developmental disorder and mental disorder
Textbook; P156-P161

15Chapter 15. Current topics on neuroscience: Animal model for brain disease and regenerative medicine