Reproductive Biology
TeachersOTA RYOMAStaffInfo
Grade, SemesterYear 3 1st semest [Department of Biosciences, Faculty of Science and Engineering]
CategorySpecial Subjects
Elective, CreditsElective 2credit
 Syllabus Number5J392

Course Description

Reproduction is essential for the continuation of a species. The applied aspects of reproductive biology have important implications for animal breeding and human clinical reproductive health. In this course, the mechanisms of animal reproduction will be lectured at molecular, cellular, and organismal levels. Furthermore, reproductive technologies used in our society will be introduced. This course aims to acquire knowledge and skills related to DP1, DP2, and DP4.

Course Objectives

The goals of this course are as follows;
1) a fundamental understanding of animal reproduction including physiology, anatomy, and endocrinology.
2) an understanding of the molecular and cellular mechanisms controlling germline cell establishment, gametogenesis, and fertilization.
3) being able to address the sexual and reproductive issues in our lives.

Grading Policy

The final grade will be evaluated based on two reports after 5th and 10th lecture (20 points each) and a final examination (60 points). A score of 60 points or more (out of 100 points) is passed. Students with attendance less than 2/3 (less than 9 lectures) will not qualify for the evaluation.
To give feedback, reports will be added comments and returned, and the answers of the final examination will be uploaded to LMS.

Textbook and Reference

TextbookThere is no specific textbook for this course. Handouts of the lecture PowerPoints will be provided.
References生殖生物学入門 UP BIOLOGY館鄰 著東京大学出版 ISBN: 9784130631327
References繁殖生物学日本繁殖生物学会 編株式会社インターズー ISBN: 9784899957881
ReferencesDevelopmental Biology 10th editionScott F. Gilbert 著株式会社メディカル・サイエンス・インターナショナル ISBN: 9784895928052


This course requires knowledge related to cell biology, molecular biology, developmental biology, and animal physiology. Review of them will help students understand the lecture in this course.
PowerPoints of the next lecture will be uploaded to LMS. Students should check and print out them before the lecture. If you have any questions about content of the lecture, please contact and ask the teacher.


I recommend that students take the courses of cell biology, molecular biology, developmental biology, and animal physiology, but it is not required.


1Introduction to reproductive biology
2Modes of reproduction
3Primordial germline cells formation
4Sex determination in somatic cells and the germline cells
5Mitosis and meiosis in the germline cells
6Testicular anatomy and spermatogenesis
7Ovarian anatomy and oogenesis
8Germline stem cell niche
9Reproductive endocrinology
10Oocyte maturation and ovulation
12Genomic imprinting
13Assisted reproductive technology
14Reproductive technologies for animal breeding
15Examination and commentary