Introduction of Organic Synthesis
TeachersUCHIDA, Kenichi
Grade, SemesterYear 3 2nd semest [Department of Biosciences, Faculty of Science and Engineering]
CategorySpecial Subjects
Elective, CreditsElective 2credit
 Syllabus Number5D363

Course Description

This course introduces the students taking this course about foundations of organic synthesis. You can acquire knowledge and ability of DP1 and DP2.

Course Objectives

The goals of this course are to be able to understand the methods of organic synthesis and to plane the synthetic route of simple organic compounds.

Grading Policy

Your overall grade in the class will be decided based on the following:
- Term-end examination: 70%
- mini-examinations: 30%

Textbook and Reference

KindTitleAuthorPublisher
Textbook"Kisokaramanabu Yuukigousei" in JapaneseLaurie S. StarkeyTokyokagakudoujin (ISBN978-4-8079-0841-7)
References

Requirements(Assignments)

Nothing in particular.

Note

Schedule

1Introduction of organic synthesis (retrosynthetic analysis, synthon, functional group inter conversion)
2Acids and bases (pKa, Luise's definition of acids and bases)
3Protective groups 1: protection of carbonyl groups and hydroxy groups
4Protective groups 2: protection of carboxyl groups and amino groups
5Functional group Inter conversion
6Redox reactions 1: oxidation reactions
7Redox reactions 2: reductive reactions
8Synthesis of alcohols and thiols
9Synthesis of alkyl halides and aryl halides
10Synthesis of ethers
11Synthesis of amines
12Synthesis of alkanes, alkenes and alkynes
13Synthesis of adehydes and ketones
14Synthesis of carboxylic acids and their derivatives
15Summary and final examination